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Department of Chemistry
Welcome to Chemistry @ NTHU


Liu, Rai-Shung
Title: Professor & Dean, College of Science    Chinese Version


Columbia University(USA)(Ph.D) (1981)
National Tsing Hua University(B.S.) (1976)

Office: Chemistry Building R509
Phone number: 33385
Web site:

Professional Experience:

1987 ~
2013 ~
2009 ~ 2012
1983 ~ 1987
1981 ~ 1982


Professor of NTHU
Dean, College of Science, NTHU
Chairman, Department of Chemistry
Associate Professor of NTHU
Postdoctoral Research,
Texas A&M University - College Station

Research Interest:

Organic, Organometallics and Inorganic

Publications:(After 2010)

  1. Diboron compound-based organic light-emitting diodes with high efficiency and reduced efficiency roll-off. Tien-Lin Wu, Min-Jie Huang, Chih-Chun Lin, Pei-Yun Huang, Tsu-Yu Chou, Ren-Wu Chen-Cheng, Hao-Wu Lin *, Rai-Shung Liu* and Chien-Hong Cheng,*Nature Photonics.2018, 12, 235.
  2. Gold-catalyzed [4+3]- and [4+2]-Annulations of 3-En-1-ynamides with Isoxazoles via Novel 6p-Electrocyclizations of 3-Azaheptatrienyl Cations.SovanSundarGiri and Rai-ShungLiu,*Chem. Sci.2018, 9, 2991.
  3. Brønsted Acids Enable Three Molecular Rearrangements of One 3-Alkylidene-2H-1,2-oxazine Molecule: Availability of Four Distinct Heterocycles from Nitroso [4+2] Cycloadditions.Bhanudas D. Mokar, Jinxian Liu and Rai-ShungLiu,*Org. Lett. 2018, 20, 1038.
  4. Gold-catalyzed N,O-functionalizations of 1,4-diyn-3-ols with N-hydroxyanilines to form highly functionalized pyrrole derivatives.Yu-Chen Hsu, Shu-An Hsieh, Po-Hsuan Li and Rai-ShungLiu,*ChemCommun.2018, 54, 2114.
  5. Gold-catalyzed Oxidative Hydroacylation Reactions of α-Iminoalkynes with Aldehydes and O2.Yu-Chen Hsu, Jing-He Lai and Rai-ShungLiu,*Chem. Commun.2017, 53, 6009.
  6. Gold-catalyzed N,O-Functionalizations of 6-Allenyl-1-ynes with N-Hydroxyanilines to Construct Benzo[b]-azepin-4-one Cores.Antony SekarKulandai Raj, Balaji S. Kale,Bhanudas D. Mokar and Rai-ShungLiu,*Org. Lett.2017, 19, 5340.
  7. Gold-catalyzed [4+2]-Annulation/Cyclization Cascades of Benzoisoxazoles with Propiolate Derivatives to Access Highly Oxygenated Tetrahydroquinolines.RajkumarLaljiSahani, and Rai-ShungLiu,*Angew. Chem. Int. Ed.2017, 56, 12736.
  8. Ground-State Dioxygen Undergoes Metal-Free [3+2]-Annulations with Allenes and Nitrosoarenes Under Ambient Conditions.Jinxian Liu,Manisha Skaria,and Rai-ShungLiu,*Chem. Science, 2017, 8, 5482.
  9. Gold-catalyzed Oxidative  [2+2+1] Annulations of Aryldiazo Nitriles with Imines to Yield PolyarylatedImidazolium Salts.Samir KundlikPawar, Ming-Chung Yang, Ming-Der Su* and Rai-ShungLiu,*Angew. Chem. Int. Ed. 2017, 56, 5035.
  10. Copper-catalyzed Three-Component Annulations of Alkenes, Nitrosoarenes and N-hydroxyallylamines to Form Fused Oxazinane/isoxazolidine Heterocycles. Rahul KisanKawade and Rai-ShungLiu,*Angew. Chem. Int. Ed. 2017, 56, 2035.
  11. Development of Gold-catalyzed [4+1] and[2+2+1]/[4+2]Annulations between Propiolate Derivatives and Isoxazoles.RajkumarLaljiSahani, and Rai-ShungLiu,*Angew. Chem. Int. Ed. 2017, 56, 1026.
  12. Two Distinct Cyclizations of 2-Propenyl-1-ethynyl benzenes with Aryldiazo Esters Using Au and Rh/Au catalysts respectively. SachinBhausahebWagh, Yu-Chen Hsu and Rai-ShungLiu,*ACS Catalysis, 2016, 6, 7160.
  13. Gold-catalyzed Intermolecular Oxidations of 2-Ketonyl-1-ethynyl benzenes with N-Hydoxyanilines to Yield 2-Aminoindenones via Gold Carbene Intermediates. BhanudasDattatrayMokar, Deepak B. Huple and Rai-ShungLiu,*Angew. Chem. Int. Ed. 2016, 55, 11892.
  14. Gold-catalyzed [3+2]-Annulations of α-Aryl Diazonitriles with Ynamides and Allenamides to Yield 1-Amino-1H-Indenes. RahulKumarRajmani Singh, Samir KundlikPawar and Rai-ShungLiu,*Chem. Commun.2016, 52, 11434.
  15. Recent Advance in Gold-Catalyzed N- and O-Functionalizations of Alkynes with Nitrones, Nitroso, Nitro and Nitroxy Species. Deepak B. Huple, Satish Ghorpade and Rai-ShungLiu,*Adv. Synth. Catal., 2016, 358, 1348. an invited review.
  16. [3+2]-Annulations of N-HydroxyAllenylamines with Nitrosoarenes: One Pot Synthesis of Substituted Indole Products. Pankaj Sharma and Rai-ShungLiu,*Org. Lett., 2016, 18(3), 412.
  17. Alkene-Directed N-Attack Chemoselectivity in the Gold-catalyzed [2+2+1]-Annulations of 1,6-Enynes with N-Hydroxyanilines.Deepak. B. Huple, Bhanudas D. Mokar and Rai-ShungLiu,*Angew. Chem. Int. Ed., 2015, 54, 14924.
  18. Gold-catalyzed Formal [4+2]-Cycloadditions of Propiolate Derivatives with Unactivated Nitriles. Somnath Narayan Karad, Wei-Kang Chung and Rai-ShungLiu,*Chemical Science, 2015, 6(10), 5964.
  19. Gold-catalyzed Cycloaddition Reactions of Ethyldiazoacetate, Nitrosoarenes and Vinyldiazo Carbonyl Compounds for the Synthesis of Isoxazolidine and Benzo[b]azepine Derivatives. Vinayak Vishnu Pagar and Rai-ShungLiu,*Angew. Chem. Int. Ed. 2015, 54,4923.
  20. Zn(II)-catalyzed Intermolecular Hydrative Aldol Reactions of 2-En-1-ynamides with Aldehydes and Water to form Branched Aldol Products Regio- and Stereoselectively.AppasoMahadevJadhav, Vinayak Vishnu Pagar, Deepak B. Huple and Rai-ShungLiu,*Angew. Chem. Int. Ed.2015, 54,3812.


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