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Department of Chemistry
Welcome to Chemistry @ NTHU


Hwang, Kuo Chu
Title: Professor                                             Chinese Versioin


Columbia University(USA)(Ph.D.) (1990)
National Tsing Hua University(M.S.) (1983)
National Cheng Kung University(B.S.) (1981)

Office: Chemistry Building B28
Phone number: 33416
Web site:

Professional Experience:

2000 ~
1993 ~ 2000
1990 ~ 1993

Professor of NTHU
Associate Professor of NTHU
Postdoctoral Research, Rockefeller University

Research Interest:

Nano-Material Chemistry、Enzyme chemistry、Organic Photochemistry


  1. RavirajVankayala and Kuo Chu Hwang*, “NIR Light ActivatableNanomaterials-Mediated PhototheranosticNanomedicines: An Emerging Paradigm for Cancer Treatment”, Adv. Mater. 2017, (in press). (SCI IF= 19.79). Invited review paper.
  2. ArunachalamSagadevan, Kuo Chu Hwang*,Ming Du Su* "Singlet Oxygen-Mediated Selective C-H Bond Hydroperoxidation of Ethereal Hydrocarbons ",Nature Comm. 2017, 8: 1812, (SCI IF= 12.1),free access at is the corresponding author for theoretical calculation.
  3. Yan-Ren Chen, Chien-Chong Hong*, Tong-MiinLiou*, Kuo Chu Hwang, and Tzung-Fang GuoRoller-Induced Bundling of Long Silver Nanowire Networks for Strong Interfacial Adhesion, Highly Flexible, Transparent Conductive Electrodes, Scientific Reports2017, 7: 16662. (SCI IF= 4.2).
  4. Ben-Yuan Li, Duane S. Juang, Avijit K. Adak, Kuo-Chu Hwang, and Chun-Cheng Lin*, Fabrication of a protein microarray by fluorous-fluorous interactions, Scientific Reports2017, 7:7053. (SCI IF= 4.2).
  5. JihRuHwu*, D. Balaji Chandrasekhar, Kuo Chu Hwang, Chun-Cheng Lin, Jia-CherngHorng and Fa-Kuen Shieh, Reductive Deamination by Benzyne for Deoxy Sugar Synthesis Through a Domino Reaction”, ChemistryOpen2017, 6, 331-335. (SCI IF= 3.58).
  6. NareshKuthala, RavirajVankayala, Yi-Nan Li, Chi-Shiun Chiang, and Kuo Chu Hwang*, “Engineering Novel Targeted Boron-10 Enriched TheranosticNanomedicine to Combat against Murine Brain Tumors via MR Imaging-Guided Boron Neutron Capture Therapy”, Adv. Mater.2017,29, 1700850.(SCI IF= 19.79)
  7. ArunachalamSagadevan, VaibhavPramodCharpe, AyyakkannuRagupathi, and Kuo Chu Hwang*, “Visible Light Copper Photoredox-catalyzed Aerobic Oxidative Coupling of Phenol and Terminal alkynes: Regioselctive Synthesis of Functionalized Ketones via CºC Triple Bond Cleavage”,J. Am. Chem. Soc.2017,139(8), 2896–2899. (SCI IF= 13.8).
  8. AyyakkannuRagupathi,VaibhavPramodCharpe, ArunachalamSagadevan, and Kuo Chu Hwang*, Visible light-mediated, Copper(I)-Catalysed Aerobic Oxidation of Ynamides/Ynamines at Room Temperature: A Sustainable Approach to Synthesis of α-Ketoimides/α-Ketoamides, Advanced Synthesis & Catalysis 2017, 359, 1138-1143(SCI IF= 5.6).
  9. Chung-Hsuan Wu, Wei-Han Wang, Chien-Chong Hong*, and Kuo Chu Hwang, A Disposable Breath Sensing Tube with On-Tube Single-Nanowire Sensor Array for On-Site Detection of Exhaled Breath Biomarkers,Lab Chip2016, 16, 4395–4405. (SCI IF= 6.0).
  10. PolirajuKalluru, RavirajVankayala, Chi-Shiun Chiang, Kuo Chu Hwang,” Unprecedented Multi-Functional Lanthanide-Doped Mesoporous Silica Frameworks for Bimodal Imaging and Chemo-Photodynamic Therapy of Tumors”, Adv. Funct. Mater. 2016, 26, 7908–7920. (SCI IF= 12.1)
  11. ArunachalamSagadevan, VaibhavPramodCharpe, and Kuo Chu Hwang*, Visible-light-mediated, copper(I)-chloride catalysedCsp-Csphomocoupling of terminal alkynes: More facile for electron withdrawing groups”,Catal. Sci. Technol. 2016, 6, 7688–7692, (SCI IF= 5.7),highlighted in the inside back cover by editor.
  12. PriyaVijayaraghavan, Cheng-Hong Liu, and Kuo Chu Hwang*, Synthesis of Multi-Branched Gold Nanoechinus using a Gemini Cationic Surfactant and its Application for Surface Enhanced Raman Scattering, ACS Appl. Mater. Interfaces2016, 8, 23909−23919;(SCI IF=7.5)
  13. Ragupathi,ArunachalamSagadevan, Chun-Cheng Lin,JihRuHwu, and Kuo Chu Hwang*, “Copper(I)-Catalysed Oxidative C-N Coupling of 2-aminopyridine with Terminal alkynes featuring an CºC bond Cleavage promoted by Visible Light”, ChemComm2016, 52, 11756 – 11759;(SCI IF= 6.3), highlighted in the inside back cover.
  14. Priya Vijayaraghavana, Chi-Shiun Chiang, Huihua Kenny Chiang, Meng-Lin Li, and Kuo Chu Hwang*, “Multi-Branched Gold Nanoechinus-Based Triple Modal Bioimaging: An Efficient NIR-to-NIR Up- and Down-conversion Emission and Photoacoustic Imaging”, Adv. Mater. Technologies2016, 1, 1600107. (SCI IF=  ); hightlighted in the Front cover.
  15. ArunachalamSagadevan, Ping-Chiang Lyu, and Kuo Chu Hwang*, “Visible-light-activatedCopper(I)-catalyzed Oxidative Csp-Csp Cross-Coupling Reaction: Efficient Synthesis of Unsymmetrical Conjugated Diynes without Ligands and Base”, Green Chem2016, 18, 4526 – 4530;highlighted in the back cover.. (SCI IF= 9.1)
  16. Sagadevan, A. Ragupathi, K. C. Hwang*,”Visible-light-induced preparation of Functionalized Indoles”, Atlas of Science 2016, June 1 issue.
  17. PolirajuKalluru, RavirajVankayala, Chi-Shiun Chiang, and Kuo Chu Hwang*, Nano-Graphene Oxide-mediatedIn vivo Fluorescence Imaging and Bimodal Photodynamic and Photothermal Destruction of Tumors, Biomaterials 2016, 95, 1-10.. (SCI IF= 8.4)
  18. Shwu-Chen Tsay *, Shu-Yu Lin, Wen-Chieh Huang, Ming-Hua Hsu, Kuo Chu Hwang, Chun-Cheng Lin, Jia-CherngHorng, I-Chia Chen, JihRuHwu *, Fa-kuenShieh, Pieter Leyssen, Johan Neyts * “Synthesis and Structure−Activity Relationship of Imidazole–Coumarin Conjugates against Hepatitis C Virus”, Molecules2016, 21, 228. (SCI IF= 2.41)
  19. ArunachalamSagadevan, AyyakkannuRagupathi, and Kuo Chu Hwang*, VisibleLight-Induced Copper-Catalyzed Three-Component Coupling of Arylamine, Terminal alkynes, and Benzoquinone: One-Step Regio-selective Synthesis of Indoles via C-H Functionalization”, Angew. Chem. Int. Ed.2015, 54, 13896–13901(5-Y IF= 11.99), ranked as “highly important” and “very important”, chosen as HOT paper and highlighted in Frontispiece.
  20. RavirajVankayala, Chien Lin Kuo, KarthikNuthalapati, Chi-Shiun Chiang, KuoChu Hwang*, “Nucleus-Targeting Multi-functional Gold Nanoclusters for Simultaneous Fluorescence Imaging, Gene Delivery and NIR Light Activated Photodynamic Therapy” Adv. Funct. Mater.2015, 25, 5934–5945;Highlighted in Frontispiece. (SCI IF= 12.1)
  21. Sharada P. Swain, Yi-Chun Shih, Shwu-Chen Tsay, Joby Jacob, Chun-Cheng Lin, Kuo Chu Hwang, Jia-CherngHorng, and JihRuHwu*, Aryne-Induced Novel Tandem 1,2-Addition/(3+2) Cycloaddition to Generate Imidazolidines and Pyrrolidines, Angew. Chem. Int. Ed.2015, 54, 9926 –9930. (SCI IF= 11.99)
  22. JihRuHwu*, MohitKapoor, Shwu-Chen Tsay, Chun-Cheng Lin, Kuo Chu Hwang, Jia-CherngHorng, I-Chia Chen, Fa-KuenShieh, Pieter Leyssen, Johan Neyts, “Benzouracil–coumarin–arene conjugates as inhibiting agents for chikungunya virus”, Antiviral Research2015, 118, 103–109.  (SCI IF= 3.8)
  23. PriyaVijayaraghavan, RavirajVankayala, Chi-Shiun Chiang, Hsing-Wen Sung, Kuo Chu Hwang*, Complete Destruction of Deep Tissue-Buried Tumors via Combination of Gene Silencing and Gold Nanoechinus-Mediated Photodynamic Therapy”, Biomaterials 2015, 62,13-23(SCI IF= 8.4).
  24. Jing-Wun Fan*, Raviraj Vankayala, Chien-Liang Chang, Chia-Hua Chang, Chi-Shiun Chiang, Kuo Chu Hwang* “ Preparation, Cytotoxicity, and in vivo Bioimaging of Highly Luminescent Water-Soluble Silicon Quantum Dots”, Nanotechnology 2015, 26, 215703 (10pp). (SCI IF= 3.8).
  25. ArunachalamSagadevan,AyyakkannuRagupathi,Chun-Cheng Lin,JihRuHwu, and Kuo Chu Hwang*Visible Light-Initiated Copper(I)-Catalyzed C-N Coupling of Aromatic Amines with Terminal Alkynes: Sustainable One Step Synthesis of α-Ketoamides using Commercial Substrates”, Green Chem. 2015, 17 (2), 1113 - 1119. (SCI IF=9.1).
  26. Kuo Chu Hwang*, and ArunachalamSagadevan, “One-Pot Room Temperature Green Conversion of Cyclohexane to Adipic Acid by Ozone/UV Light”,Science2014, 346, 1495-1498.(5-Y IF=37.2).Highlighted in Chemistry World, Scientific American, C&EN, ScienceNews, Phys.Org, etc.  PDFLink
  27. Kuo Chu Hwang* and PeriyasamyMurugan*, “Synthesis of P38 MAP kinase Inhibitor Analogues Compounds and Quinoxalinone Derivatives”, Int. J. Pharma and Bio Sciences 2014, 5(4), 212 -224.
  28. PeriyasamyMurugan* and Kuo Chu Hwang*, “Efficient green light-emitting diodes based on substituted triphenylamine derivatives”, Int. J. ChemTech Research2014, 6 (7), 3518-3526.
  29. PriyaVijayaraghavan, Cheng-Hong Liu, RavirajVankayala, Chi-Shiun Chiang, Kuo Chu Hwang*, “Designing Multi-branched Gold Nanoechinus for NIR Light Activated Dual Modal Photodynamic and Photothermal Therapy in the Second Biological Window”, Adv. Mater.2014, 26, 6689–6695. (5-Y IF= 19.79). Highlighted as Frontispiece, Highlighted by Asian Scientist magazine.
  30. Avijit K. Adak, Ben-Yuan Li, Li-De Huang, Ting-Wei Lin, Tsung-Che Chang, Kuo Chu Hwang, and Chun-Cheng Lin*, “Fabrication of antibody microarrays by lightinduced covalent and oriented immobilization”, ACS Applied Materials & Interfaces2014, 6, 10452-10460. (SCI IF=7.5).
  31. RavirajVankayala, Chi-Shiun Chiang, Chiun-Jye Yuan, Jui-I Chao, Shyr-Yeu Lin, and Kuo Chu Hwang*, “A General Strategy to Achieve Ultra-High Gene Transfection Efficiency using Lipid-Nanoparticle composites”, Biomaterials2014, 35(28), 8261-8272. (SCI IF= 8.4).
  32. RavirajVankayala, Chun-Chih Lin, PolirajuKalluru, Chi-Shiun Chiang, and Kuo Chu Hwang*, “Gold Nanoshells-Mediated Bimodal Photodynamic and Photothermal Cancer Treatment Using Ultra-Low Doses of Near Infra-red Light”,Biomaterials2014, 35(21), 5527-5538. (SCI IF= 8.4)
  33. RavirajVankayala, Yu-Kuan Huang, PolirajuKalluru, Chi-Shiun Chiang, Kuo Chu Hwang*, “First Demonstration of Gold Nanorods-Mediated Photodynamic Therapeutic Destruction of Tumors via Near Infra-Red Light Activation”, Small2014, 10(8), 1612–1622. (SCI IF= 8.6), Highlighted by Nanowerk, Future Med Chem. (2014) 6(4), 370 and The #1 Antibody Resource website.
  34. RavirajVankayala, PolirajuKalluru, Hsin-Hui Tsai, Chi-Shiun Chiang, and Kuo Chu Hwang*,“Effects of Surface Functionality of Carbon Nanomaterials on Short-Term Cytotoxicity and Embryonic Development in Zebrafish“, J. Mater. Chem. B 2014, 2 (8), 1038 - 1047(5-Y IF= 4.72)
  35. Shengqin Wang, Zi-Xiang Lin,Wei-Han Wang, Chien Lin Kuo, Kuo Chu Hwang*,Chien-Chong Hong*, Self-regenerating Photocatalytic Sensor Based on Dielectrophoretically Assembled TiO2 Nanowires for Chemical Vapor Sensing”,. Sensors and Actuators B: Chem. 2014, 194, 1– 9.(SCI IF=3.83).
  36. Chin-Feng Wan*, Chao-Sheng Chen, Kuo-Chu Hwang, Yen-Han Lai, Jhang-Yun Luo, Po-Ching Liu, Long-Sheng Fan*,Development and Automation of Microelectromechanical Systems-Based Biochip Platform for Protein Assay”, Sensors & Actuators B: Chem. 2014, 193, 53-61.(SCI IF=3.83).
  37. PolirajuKalluru, RavirajVankayala, Chi-Shiun Chiang‍‍, Kuo Chu Hwang*,”Photo-sensitization of singlet oxygen and Photodynamic Therapeutic Effects Mediated by PEGylated W18O49 Nanowires on Destruction of Tumors”, Angew. Chem. Int. Ed.2013, 52(47), 12332-12336.Highlighted in inside back cover. (5-Y IF= 11.99).
  38. ArunachalamSagadevan,AyyakkannuRagupathi, and Kuo Chu Hwang*, “Visible-light Induced Copper (I) Catalyzed Oxidative Diamination of Terminal Alkynes by o-Phenylenediamine: One-Pot Synthesis 3-Phenyl-2-hydroxy-quinoxaline”, Photochem. Photobiol. Sci. 2013, 12 (12), 2110 - 2118, (SCI IF= 2.92) invited paper in a memorial issue dedicated to the late professor N. J. Turro, 
  39. RavirajVankayala, Chien-Lin Kuo, ArunachalamSagadevan, Po-Hung Chen, Chi-Shiun Chiang and Kuo Chu Hwang*, “Morphology Dependent Sensitization and Formation of Singlet Oxygen (1Δg) by Gold and Silver Nanoparticles and its Application in Cancer Treatment”, J. Mater. Chem. B.2013, 1, 4379-4387.(5-Y IF= 4.72), selected as HOT article by editor for 2013.
  40. Shwu-Chen Tsay, JihRuHwu, RaghunathSingha, Wen-Chieh Huang, Yung Hsiung Chang, Ming-Hua Hsu, Fa-kuenShieh, Chun-Cheng Lin, Kuo Chu Hwang, Jia-CherngHorng, Erik De Clercq, IngeVliegen, Johan Neyts, “Coumarinshinged directly on benzimidazoles and their ribofuranosides to inhibit hepatitis C virus”, Euro. J. Med. Chem. 2013, 63, 290-298.  (SCI IF= 3.43) 
  41. Congxin Dai, FengCai, Kuo Chu Hwang, Yongmao Zhou, Zizhu Zhang, Xiaohai Liu, Sihai Ma, Yakun Yang, Yong Yao, Ming Feng, XinjieBao, Guilin Li, Junji Wei, Yonghui Jiao, Zhenqing Wei, Wenbin Ma, Renzhi Wang, "Folate receptor-mediatedboron-10 containing carbon nanoparticles as potential delivery vehicles for boron neutron capture therapy of nonfunctional pituitary adenomas”, Science China Life Sciences 2013, 56(2), 163-173.(SCI IF= 1.345).
  42. Chein Lin Kuo, and Kuo Chu Hwang* “ Does Morphology of a Metal Nanoparticle Play a Role in Ostwald Ripening Processes?”, Chem. Mater.2013, 25(3), 365-371. (SCI IF= 9.46).
  43. ArunachalamSagadevan, and Kuo Chu Hwang*,“Photo-induced Sonogashira C-C Coupling Reaction Catalyzed by Simple CuCl Salt at Room Temperature”,Advanced Synthesis & Catalysis2012, 354 (18), 3421-3427. (SCI IF=5.6).
  44. K. S. Prasad, Nien-Chu Fan, Li-Chen Wu, Heng-Chia Chang, Li-Sheng Wang, Kuo-Chu Hwang, Reuben Jih-RuHwu, Jia-CherngHorng, Chun-Cheng Lin and Ja-an Annie Ho*, “A Tunable Multicolor PhotoluminescentNanocarbon Prepared from Castor Oil Soot”, J. Chin. Chem. Soc.2012, 59, 802-808.(SCI IF= 0.65).
  45. Z. Y. Lien, T. C. Hsu, K. K. Liu, W. S. Liao, K. C. Hwang, and J. I. Chao*, “Cancer cell labeling and tracking using fluorescent and magnetic nanodiamond”, Biomaterials2012, 31, 6172-6185.(5-Y IF= 8.97).
  46. PradipKundu, and Kuo Chu Hwang*, “Rational Design of Phosgene Fluorescence Sensors”, Anal. Chem.2012,84, 4594-4597. (5-Y IF= 5.79), Highlighted by C&EN, 2012-04-17.5-Y IF=5.98.
  47. Chien Lin Kuo, and Kuo Chu Hwang*, "Self-Assembly of Silver Nanoparticles and Nanorods to Form Strained Long Nanowires: A New Nanowire Growth Mechanism",Langmuir2012, 28, 3722-3729.(SCI IF= 4.18).
  48. Chung-Liang Wang, Lan-Yi Wei, Chiun-Jye Yuan* and Kuo Chu Hwang, “Reusable amperometric biosensor for measuring protein tyrosine kinase activity”, Anal. Chem.2012, 84, 971-977. (5-Y IF=5.79)
  49. Chun-Chih Chang, L. W. Wang, Y. H. Chen, Kuo Chu Hwang, Jwo-HueiJou, Y. S. Chang, Arnold C.-M. Yang*, “White Luminescent Polymers by Plasma Polymerized Iridium Complexes from 1,10-phenanthrolin”. Plasma Process Polym.2012, 9, 225-233. (SCI IF=2.46).
  50. RavirajVankayala, ArunachalamSagadevan, PriyaVijayaraghavan, Chien Lin Kuo, Kuo Chu Hwang*, “Metal Nanoparticles Sensitize Formation of Singlet Oxygen”, Angew. Chem. Int. Ed .2011, 50, 10640-10644. (5-YIF= 12.1).
  51. K. P. Tung, C.-H. J. Tsao, T. M. Hong, K. C. Hwang, J.-H. Hsu, J. D. White, and A. C. M. Yang*, Dramatic Photoluminescence Enhancements of Conjugated Polymers by Molecular Constraints via Mechanical Stretching, ACS Nano2011, 5, 7296-7302. (5-YIF= 14.48).
  52. RavirajVankayala, Wei-jenPetrick Lai, Kuo-Chung Cheng,and Kuo Chu Hwang*, "Enhanced electrical conductivity of nylon 6 composite using polyaniline-coated multi-walled carbon nanotubes as additives", Polymer2011, 52, 3337-3343. (SCI IF= 3.8).
  53. Chun-Chih Chang, Yi-Hsin Chang, Kuo Chu Hwang, Jwo-HueiJou, Arnold C.-M. Yang*, “One-step fabrication of π-conjugated polymer thin films from naphthalenes via plasma polymerization for efficient optoelectronic devices: white polymer light-emitting diodes”. Plasma Process Polym.2011, 8, 215-223. (SCI IF=2.46).
  54. C. C. Chen, W. Hsu., K. C. Hwang, J. R. Hwu, C. C. Lin, J. C. Horng*, Contributions of Cation-pi interactions to the collagen triple helix stability. Arch. Biochem. Biophys. 2011, 508, 46-53. (SCI IF= 3.046).
  55. Lin Ai Tai and Kuo Chu Hwang* “Regulation of Xanthine Oxidase Activity by Substrates at Active Sites via Cooperative Interactions between Catalytic Subunits: Implication to Drug Pharmacokinetics”, Current Medicinal Chemistry2011, 18, 69-78(SCI IF= 4.85).
  56. Chiun-Jye Yuan*, Chung-Liang Wang, Teng Yang Wu, Kuo Chu Hwang, and Wei-Chi Chao. Fabrication of a carbon fiber paper as the electrode and its application toward developing a sensitive unmediated amperometric biosensor. Biosensors andBioelectronics2011, 26, 2858-2863. (SCI IF= 5.6)
  57. Kuo Chu Hwang*, "Recent Progress in the Preparation and Applications of Carbon Nanoocapsules", J. Phys. D: Appl. Phys.2010, 43, 374001 (13pp) (invited review). (SCI IF= 2.1).
  58. Kuo Chu Hwang*, Po Dong Lai, Chi-Shiun Chiang, Pei-Jen Wang, Chiun-Jye Yuan "Neutron Capture Elements-Containing Carbon Nanoparticles for Destruction of Cancer Cells ", Biomaterials 2010, 31,8419-8425.(5-Y IF= 8.97).
  59. Chang-Ching Lin, Nai-Pin Lin, L. SkSahabuddin, VijayaRaghava Reddy, Li-De Huang, Kuo Chu Hwang, and Chun-Cheng Lin*,”5-N,4-O-Carbonyl-7,8,9-tri-O- chloroacetyl-Protected Sialyl Donor fortheStereoselective Synthesis of r-(2f9)-Tetrasialic Acid”, J. Org. Chem.2010, 75(15), 4921-28. (SCI IF= 4.21)
  60. Qingxin Mu, Lei Yang, James C. Davis, RavirajVankayala, Kuo Chu Hwang, Jincai Zhao and Bing Yan* “Biocompatibility of Polymer Grafted Core/Shell Iron/Carbon Nanoparticles ", Biomaterials2010, 31, 5083-5090. (5-Y IF= 8.97).
  61. Ja-an Annie Ho, Li-ChenWu, Li-Hui Chang, Kuo Chu Hwang, Jih-Ru Reuben Hwu, “Liposome-based immunoaffinity chromatographic assay for the quanitation of immunoglobulin E in human serum”, J. Chromatography B-Analytical Technologies in The Biomedical and Life Sci. 2010, 878, 172-176.  (SCI IF= 2.50).
  62. In Pin Chang, Kuo Chu Hwang*, Ja-an Annie Ho, Chun-Cheng Lin, Reuben J.-R. Hwu, Jia-CherngHorng, "Facile Surface Functionalization of Nanodiamonds", Langmuir, 2010, 26(5), 3685–3689. (SCI IF=4.0).
  63. Kuo Chu Hwang*, "Light-absorbing Materials and Applications", Taiwan patent application number: 094130138, patent allowed, Oct. 18, 2009
  64. Huang, J. J.-T.; Tsai, F.-Y.; Tsay, S.-C.; Hsu, M.-H.; Hwang, K. C.; Horng, J.-C.; Ho, J. A.; Lin, C.-C.; Hwu, J. R.* "Photochemical Activities of N-NitrosoCarboxamides and Sulfoximides as well as Their Application to DNA Cleavage" Chem. Euro. J.2009, 15, 8742-8750. (SCI IF= 5.92). Cover page article.
  65. Ja-an Annie Ho*, Yeh-Chun Lin, Li-Sheng Wang, Kuo Chu Hwang, Pi-Tai Chou, "Carbon Nanoparticle Enhanced Immunoelectrochemical Detection for Protein Tumor Marker with Cadmium Sulfide Biotracers", Anal. Chem.2009, 81, 4, 1340-1346. (SCI IF= 5.85).
  66. Ho, J.-A. A.*; Chiu, J.-K; Hsu, W.-L.; Hong, J.-C.; Lin, C. C.; Hwang, K.-C.; Hwu, J. R. "Gold-Nanostructured Immunosensor for the Electrochemical Sensing of Biotin Based on Liposomal Competitive Assay" J. Nanosci. Nanotech.2009, 9, 2324-2329. (SCI IF 1.56).
  67. Mu-Lin Chen, Avijit Kumar Adak, Nai-Chia Yeh, Wen-Bin Yang, Yung-Jen Chuang, Chi-Huey Wong, Kuo Chu Hwang, Jih-Ru Reuben Hwu, Shih-Liang Hsieh, Chun-Cheng Lin*, "Fabrication of an Oriented Fc-Fused Lectin Microarray through Boronate Formation",AngewChemInt Ed Engl. 2008, 47, 8627-8630. (5-Y IF= 12.1)
  68. In Pin Chang, Kuo Chu Hwang*, Chi-Hsin Chiang, "Preparation of Fluorescent Magnetic Nanodiamonds and Cellular Imaging", J. Am. Chem. Soc.2008,130, 15476-15481. (SCI IF 9.9) Highlighted in Nature Publishing Group (NPG) Asia Materials for the best research published in the field of materials science by researchers in the Asia-Pacific region, Dec 2008.
  69. Yu-Lin Hsin, Chia-Fen Lin, Yu-Chia Liang, Kuo Chu Hwang*, Jia-CherngHorng, Ja-an Annie Ho, Chun-Cheng Lin, Reuben J.-R. Hwu, "Microwave Arcing Induced Formation and Growth Mechanisms of Core-shell Metal/carbon Nanoparticles in Organic Solutions", Adv. Funct. Mater.,2008, 18, 2048--2056. (SCI IF= 10.17) Cover page article.
  70. Yu-Chia Liang, Kuo Chu Hwang*, Shen-Chuan Lo, "Solid State Microwave Arcing Induced Formation and Surface Functionalization of Core-Shell Metal/Carbon Nanoparticles.", Small 2008, 4, 405-409. (5-Y IF= 8.3)
  71. Yu Lin Hsin, Kuo Chu Hwang* and Chuin-TihYeh, “Poly(vinyl pyrrolidone) Modified Graphite Carbon Nanofibers as Promising Supports for PtRu Catalysts in Direct Methanol Fuel Cells.”, J. Am. Chem. Soc.2007, 129, 9999-10010. (SCI IF 9.9)Times Cited:309
  72. Chun Chih Tong, and Kuo Chu Hwang*, "Enhancement of OLED Efficiencies and High Voltage Stabilities by Deuteration of Light Emitting Materials ", J. Phys. Chem. C.2007. 111, 3490-3494.  (SCI IF= 4.8)
  73. Qin-Hua Song, Kuo Chu Hwang*, "Direct observation for photophysical and photochemical processes of folic acid in DMSO solution", J. Photochem. Photobiol. A: Chem.2007, 185, 51–56. (SCI IF 2.286)
  74. Kuo Chu Hwang*, Yu Lin Hsin, Jyun-Yi Lai, "Application of nano-materials in biomedical diagnosis", Chemistry (The Chinese Chem. Soc. Taipei) June2006, 64 (2), 179-190. (invited review).
  75. Yu Lin Hsin, Jyun-Yi Lai, Kuo Chu Hwang*, Shen-Chuan Lo, Fu-Rong Chen, and J. J. Kai, "Rapid Surface Functionalization of Fe-Filled Multi-walled Carbon Nanotubes", Carbon2006, 44, 3328-3335. (SCI IF 5.37).
  76. P. Murugan, Kuo Chu Hwang, V. T. Ramakrishnan and S. Balasubramanian, " Facile Synthesis of Electroluminescence Acridinedions by Microwave and Ultrasound", AZojomo-J. Materials online, 2005, 1, 1-7.
  77. Yeong-TarngShieh*, Gin-Lung Liu, Kuo Chu Hwang, and Chia-Chun Chen," Enhancement of PEO Crystallization in PEO/MWNTs-g-PMMA Blends", Polymers2005, 46, 10945-10951.(SCI IF 3.43).
  78. Shu-Wen Yang, ArumugasamyElangovan, Kuo Chu Hwang, and Tong-Ing Ho*," Electronic Polarization Reversal and Excited State Intramolecular Charge Transfer in Donor/Acceptor EthynylPyrenes", J. Phys. Chem. B2005, 109, 16628-16635. (SCI IF 3.69)
  79. PeriyasamyMurugan, Kuo Chu Hwang, DhakshanamurthyThirumalai*, and Vayalakavoor T. Ramakrishnan, "A facil and simple route to the synthesis of condensed acridine systems", Synthetic Comm. 2005, 35, 1781-1788.  (SCI IF 1.06).
  80. Y.-L. Chen, S.-W. Lee, Y. Chi*, Kuo Chu Hwang, S. B. Kumar, Y.-H. Hu, Y.-M. Cheng, P.-T. Chou, S.-M. Peng, G.-H. Lee, C.-T. Chen and S.-J. Yeh, "Synthesis, Characterization and Photophysical Properties of Os(II) Diimine Complexes [Os(N^N)(CO)2I2], NN = Bipyridine, Phenanthroline and PyridylBenzoxazole", Inorg. Chem.2005, 44, 4287-4294. (SCI IF 4.12).
  81. U-SerJeng*, Chia-Hung Hsu, Tsang-Lang Lin, Ching-Mao Wu, Hsin-Lung Chen, Lin-Ai Tai, and Kuo Chu Hwang, "Dispersion of fullerenes in phospholipid bilayers and the subsequent phase changes in the host bilayers", Physica B: Physics of Condensed Matter,2005, 357, 193-198. (SCI IF 1.06).
  82. Gan Lin Hwang, Yeong-TarngShieh*, Kuo Chu Hwang*, “Efficient load transfer to polymer chain grafted carbon nanotubes in composite polymers”, Adv. Functional Mater.2004,14(5), 487-491.  (SCI IF 9.76) Times Cited: 194
  83. Lin Ai Tai, Kuo Chu Hwang*, “Cooperative Inhibition in Xanthine Oxidase Homodimer Subunits”, Biochemistry2004, 43, 4869. (SCI IF 3.42)
  84. Ya-Wen Chen, Kuo Chu Hwang, Cheng-Chieh Yen, and Yih-Loong Lai*, “Fullerene derivatives protect against oxidative stress in RAW 264.7 cells and ischemia-reperfused lungs”, Am J PhysiolRegulIntegr Comp Physiol,2004,287: R21-R26. (SCI IF 3.33)
  85. P. Murugan, Kuo Chu Hwang*, V. T. Ramakrishnan, S. Balasubramanian, “Facile Synthesis of Electroluminescence Materials, Acridinediones”, Advances in Technology of Materials and Materials Processing Journal 2004, 6(1), 37-42.
  86. Aminul Islam, PeriyasamyMurugan, Kuo Chu Hwang*, Chien-Hong Cheng, “Blue light-emitting devices based on 1,8-acridinedione derivatives”, Synthetic Metals2003,139 (2), 347-353.  (SCI IF 1.82)
  87. Gan Lin Hwang, Kuo Chu Hwang*, Yeong-TarngShieh, S. J. Lin “ Preparation of carbon nanotubes encapsulated copper nanowires and their use as a reinforcement for Y-Ba-Cu-O superconductors”, Chem. Mater.2003, 15, 1353-1357. (5-Y IF=9.3)
  88. SudhirRanjan, Shen Yi Lin, Kuo Chu Hwang*, Yun Chi*, Wei-Li Ching, Chao-Shiuan Liu, Yu-Tai Tao, Chin-HsiungChien, Shie-Ming Peng and Gene-Hsiang Lee, “Realizing Green Phosphorescent Light-Emitting Materials from Rhenium(I) PyrazolatoDiimine Complexes”,Inorg. Chem.2003, 42, 1246-1255. (SCI IF 4.6) Times Cited: 140
  89. Y.-L. Lai, P. Murugan, K.C. Hwang*, “Fullerene derivative attenuates ischemia-reperfusion-induced lung injury”, Life Sci. 72: 1271-1278, 2003. (SCI IF 2.52)
  90. Q. H. Song &K. C. Hwang*, “Reaction Mechanism of Photoenzymes”, Chemistry (The Chin Chem. Soc., Taipei, in Chinese, invited review), 2002, 60, 621-629.
  91. S. F. Tzeng*, J. L. Lee , J. S. Kuo, C. S. Yang, P. Murugan, L. A. Tai, K. C. Hwang,"Effects of malonate C-60 derivatives on activated microglia", Brain Research2002, 940 (1-2): 61-68. (SCI IF 2.72).
  92. Sen Chin Kung, Kuo Chu Hwang*, I. N. Lin,“O2 and O3 Oxidation Enhanced Field Emission of Carbon Nanotubes, Appl. Phys. Lett..2002, 80, 4819-4821. (SCI IF 3.84).
  93. Kuo Chu Hwang*, “Carbon nanotubes as field emitters for flat panel displays”, Chemical Engineering2002, 49(1), 43-52. (Invited review).
  94. Che-Hao Chang, Kuo Chu Hwang, Chao-Shiuan Liu, Yun Chi*, Arthur J. Carty,  LudmilaScoles, Shie-Ming Peng, Gene-Hsiang Lee, and Jan Reedijk, “Unique formation and stabilization of a decanuclear Cu(II) wheel linked by chloride and O¼H-N Hydrogen bonds”, Angew. Chem. Int. Ed. Engl. 2001, 40, 4651-4653. (SCI IF 13.45).
  95. IngChe Kao, Yu Lin Hwang,Cheu-PyengCheng,Wen-JwuWang, Bo-Cheng Wang,Kuo Chu Hwang*,"Production of Carbon Nanotubes in Air”, Fullerene Science & Technology2001, 9 (3), 321-328. (SCI IF 0.85)Times Cited:3
  96. Gan Lin Hwang, Kuo Chu Hwang*,"Breakage, Fusion, and Healing of Carbon Nanotubes, Nano Lett.2001, 1, 435-438. (SCI IF 13.2).
  97. Y. L. Hsin, K. C. Hwang*, Fu-Rong Chen, J. J. Kai, "Production and in situ metal filling of carbon nanotubes in water", Adv. Mater.2001, 13, 830-833. (SCI IF 13.87) Times Cited: 129
  98. Gan Lin Hwang, Kuo Chu Hwang*,"Carbon Nanotubes Reinforced Ceramics", J. Mater. Chem. 2001, 11, 1722-1725. (SCI IF 5.96)
  99. Lin Ai Tai,Kuo Chu Hwang*, "Photo Reactivation of Alloxanthine Inhibited Xanthine Oxidase", Photochem. Photobiol., 2001, 73, 439-446. (SCI IF 2.41).
  100. Kuo Chu Hwang*,“ Development and Applications of Carbon Nanotubes” (invited paper, in Chinese), Natural Sciences Newsletter, NSC2000,12(2), 60-62.
  101. D. Samuel, T. K. S. Kumar, G. Ganesh, G. Jayaraman, P. W. Yang, V. Trivedi, S. L. Wang, K. C. Hwang, D. K. Chang, C. Yu*, "Proline Inhibits Aggregation during Protein Refolding", Protein Science, 2000, 9(8), 1604-1604. (SCI IF 2.79)
  102. Lin Ai Tai, Kuo Chu Hwang*,"Control of Xanthine Oxidase Activity by Light", Angew. Chem. Int. Ed. Engl., 2000, 39 (21), 3886-3888.  (SCI IF 13.4)
  103. D. Samuel, T. K. S. Kumar, G. Ganesh, G. Jayaraman, P. W. Yang, V. Trivedi, S. L. Wang, K. C. Hwang, D. K. Chang, C. Yu*, "Proline Inhibits Aggregation during Protein Refolding”, Protein Science, 2000, 9(2), 344-352. (SCI IF 2.79)Times Cited: 153
  104. I Chen Wang, Lin Ai Tai, Don Dar Lee, P. P. Kanakamma, Clifton, K. -F. Shen, TienYauLuh, Chien Hong Cheng, Kuo Chu Hwang*,"C60 and Water Soluble fullerene Derivatives as Antioxidants against Radical Initiated Lipid Peroxidation", J. Med. Chem.,1999, 42, 4614-4620. (SCI IF 5.24) Times Cited: 176
  105. Y. L. Hwang, and K. C. Hwang*,“Nonlinear Stern-Volmer fluorescence quenching of pyrene by C60/70",FULLERENE SCIENCE AND TECHNOLOGY,1999, 7(3), 437-454. (SCI IF 1.0).
  106. Yu-Lun Huang, Clifton K. F. Shen, Tien-YauLuh, Hong Chou Yang, Kuo Chu Hwang, Chen Kung Chou*,"Selective Blockage of Apoptotic Signaling of Transforming Growth Factor-b by Bcl-2 and Carboxyfullerene in Human Hepatoma cells", Euro. J. Biochem.1998, 254, 38-43.   (SCI IF 3.25)
  107. Yu Lien Hwang, and Kuo Chu Hwang*,"Photophysical and Photochemical Studies of C60 by ESR spectroscopy" (invited paper, in Chinese), Chemistry (The Chinese Chem. Soc., Taipei) 1997, 55, pp53-58.
  108. Yu Lien Hwang, CheChau Yang, and Kuo Chu Hwang*,"Origin of the Spike in the C60-. ESR Spectrum: Oxygen Effect and Negative Temperature Dependence of the C60O2-. Isomerization Rate", J. Phys. Chem. A 1997, 101, 7971-7976. (SCI IF 2.94)
  109. Kuo Chu Hwang*,“Developments of Molecular Electronics" (invited paper, in Chinese), Natural Science Newsletter, NSC, 1996, 8(1) 16-19.
  110. C. C. Yang, and K. C. Hwang*, “Disproportionation of Photo Excited C60", J. Am. Chem. Soc. 1996, 118, 4693. (SCI IF 9.9)
  111. K. C. Hwang*,“Efficient cleavage of carbon graphene layers by oxidants", J. Chem. Soc. Chem. Comm.1995, 173.
  112. K. C. Hwang*,“High yield conversion of carbon nanotubes to nanostraws at mild conditions", SCIENCE AND TECHNOLOGY OF FULLERENE MATERIALS  Book Series: MRS SYMPOSIUM PROCEEDINGS   Volume: 359   Pages: 75-80   Published: 1995.
  113. K. C. Hwang, S. Niu, D. Mauzerall*, Electron Transfer Across a Lipid Bilayer Mediated by Fullerenes.  In Recent Advances in the Chemistry and Physics of Fullerenes and Related Materials.  K. M. Kadish, and R. S. Ruoff, Eds., The Electrochemical Society, Inc., Pennington, NJ, 1994, pp845~853.
  114. K. C. Hwang*, N. J. Turro*, and H. D. Roth,"Hydrogen donating solvent participation in the photochemistry of benzaldehyde and deoxybenzoin- A 13C CIDNP study", J. Org. Chem. 1994, 59, 1102-1107.  (SCI IF 4.45)
  115. K. C. Hwang, D. Mauzerall*, R. W. Wagner, and J. S. Lindsey, "Synthesis of amphipathic porphyrins and their photoinduced electron transfer reactions at the lipid bilayer-water interface", Photochem. Photobiol. 1994, 59, 145-151.(SCI IF 2.41)
  116. K. C. Hwang, and D. Mauzerall*,“PhotoinducedTransmembrane Electron Transport Mediated by C70 Anion", Nature. 1993, 361, 138. (SCI IF 36.28), Times Cited: 140
  117. K. C. Hwang, and D. Mauzerall*,“Vectorial Electron Transfer from an Interfacial PhotoexcitedPorphyrin to Ground State C60 and C70 and from Ascorbate to Triplet C60 and C70 in a Lipid Bilayer", J. Am. Chem. Soc.1992, 114, 9705.  (SCI IF 9.9), Times Cited: 78
  118. K. C. Hwang, H. D. Roth, N. J. Turro*, and K. M. Welsh,“Enhancement or Suppression of CIDNP Intensities by a 2nd Magnetic Nucleus-Interplay between g-Factor Defference External Magnetic Field, and Hyperfine Coupling Constants”, J. Phys. Org. Chem. 1992, 5, 209.  (SCI IF 1.96)
  119. N. Han, K. C. Hwang, X. Lei, and N. J. Turro*,“Photochemistry of 2,2',12-Trimethyl- cyclododecanone and 2,2',12,12'-tetramethylcyclododecanone: Product Distribution, Photo-CIDNP, and Magnetic Isotope Effect",  J. Photochem..Photobiol. A. Chem., 1991, 61, 35. (SCI IF 2.41)
  120. N. J. Turro*, K. C. Hwang, V. P. Rao, and C. Doubleday, Jr., “Utilization of Radical Scavenging to Develop Nuclear Spin Polarization and Magnetic Isotope Separation in Long Flexible Biradicals”, J. Phys. Chem. 1991, 95, 1872.  (SCI IF 4.17)
  121. K. C. Hwang, N. J. Turro*, and C. Doubleday, Jr., “Investigation of the Kinetic Window for Generationof13C T0 - S CIDNP Derived from Long-Chain Biradicals by Tuning the Rates of Bimolecular Scavenging and Intersystem Crossing”, J. Am. Chem. Soc. 1991, 113, 2850.  (SCI IF 9.9)
  122. K. C. Hwang, N. J. Turro*, C. H. D. Roth, and C. Doubleday, Jr., “Suppression of Chemically Induced Dynamic Nuclear Polarization Enhancements by Nuclei with Large Hyperfine Coupling Constants”, J. Phys. Chem. 1991, 95, 63.  (SCI IF 4.17)
  123. H. D. Roth, R. S. Hutton, K. C. Hwang, N. J. Turro*, and K. M. Welsh, “Chemically Induced Dynamic Nuclear Polarization in Systems Containing Large Hyperfine Coupling Constants”, J. Phys. Chem., 1989, 93, 5697.  (SCI IF 4.17)
  124. N. J. Turro*, C. Doubleday, Jr., K. C. Hwang, C. C. Cheng, and J. R. Fehlner,  “Magnetic Isotope Effects in Biradicals:  Substantial 13C Enrichment and a Novel Mechanistic Probe”, Tetrahedron Lett., 1987, 28, 2929.  (SCI IF 2.68)
  125. K. S. Arora, K. C. Hwang, and N. J. Turro*, “Photophysical Investigation of the Interactions of Phospholipids and a Pyrene Substitute Poly   (acrylic acid) in Dilute Solutions”, Macromolecules, 1986, 19, 2806.  (SCI IF 5.16)
  126. Kuo Chu Hwang*, “ Application of Simplex Optimization Technique in Chemical Data Processing, Instruments Today1985, 6(4), 45-53. (invited paper, in Chinese)
  127. H. Chang* and K. C. Hwang, “The Behavior of Pyridine, Pyridinium Ion, and Pyridinium Halide on a Ag Electrode and Their SERS Spectra”, J. Am. Chem. Soc., 1984, 106, 6586.  (SCI IF 9.9)
  128. K. C. Hwang and H. Chang*,“The SERS of Pyridine on an Electro-chemically Plated Silver Electrode”, Chem. Phys. Lett., 1983, 98, 597.(SCI IF 2.33)


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