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Department of Chemistry
Welcome to Chemistry @ NTHU


Hwang, Kuo Chu
Title: Professor                                             Chinese Versioin


Columbia University(USA)(Ph.D.) (1990)
National Tsing Hua University(M.S.) (1983)
National Cheng Kung University(B.S.) (1981)

Office: Chemistry Building B28
Phone number: 33416
Web site:

Professional Experience:

2000 ~
1993 ~ 2000
1990 ~ 1993

Professor of NTHU
Associate Professor of NTHU
Postdoctoral Research, Rockefeller University

Research Interest:

Nano-Material Chemistry、Enzyme chemistry、Organic Photochemistry


  1. Arunachalam Sagadevan, V. Kishore Kumar Pampanaand Kuo Chu Hwang*, Visible-Light-driven Copper Photoredox-catalyzed Multicomponent Coupling of Arylamines, Terminal Alkynes, and Alcohols via a HAT process.Angew. Chem. 2019 (in press)(SCI IF= 12.1)
  2. Deb Kumar Das, V. Kishore Kumar Pampana and Kuo Chu Hwang*, “Copper Catalyzed Photoredox Synthesis of a-Keto Esters, Quinoxaline, Naphthoquinone: Controlled Oxidation of Terminal Alkynes to Glyoxals”, Chemical Science20189, 7318-7326. (SCI IF= 9.0). highlighted in inside back cover.
  3. Vaibhav Pramod Charpe, Aniket A. Hande, Arunachalam Sagadevan, and Kuo Chu Hwang*, “Visible-Light Induced Copper(I)-CatalysedDenitrogenative Oxidative Coupling of hydrazinylpyridines with Terminal Alkynes”, Green Chemistry201820, 4859 - 4864, highlighted in inside back cover. (SCI IF=8.58)
  4. Raviraj Vankayala and Kuo Chu Hwang*, “NIR Light Activatable Nanomaterials-Mediated Phototheranostic Nanomedicines: An Emerging Paradigm for Cancer Treatment”, Adv. Mater. 201830, 1706320, DOI:10.1002/adma.201706320 (SCI IF= 21.9). Invited review paper
  5. Arunachalam Sagadevan, Kuo Chu Hwang*, Ming Du Su* "Singlet Oxygen-Mediated Selective C-H Bond Hydroperoxidation of Ethereal Hydrocarbons ", Nature Comm20178: 1812, (SCI IF= 12.3),free access at  MDS is the corresponding author for theoretical calculation.
  6. Yan-Ren Chen, Chien-Chong Hong*, Tong-MiinLiou*, Kuo Chu Hwang, and Tzung-Fang GuoRoller-Induced Bundling of Long Silver Nanowire Networks for Strong Interfacial Adhesion, Highly Flexible, Transparent Conductive Electrodes, Scientific Reports 20177: 16662. (SCI IF= 4.2).
  7. Ben-Yuan Li, Duane S. Juang, Avijit K. Adak, Kuo-Chu Hwang, and Chun-Cheng Lin*, Fabrication of a protein microarray by fluorous-fluorous interactions, Scientific Reports 2017, 7:7053. (SCI IF= 4.2).
  8. Jih Ru Hwu*, D. Balaji Chandrasekhar, Kuo Chu Hwang, Chun-Cheng Lin, Jia-CherngHorng and Fa-Kuen Shieh, Reductive Deamination by Benzyne for Deoxy Sugar Synthesis Through a Domino Reaction”, ChemistryOpen 2017, 6, 331-335. (SCI IF= 3.58).
  9. Naresh Kuthala, Raviraj Vankayala, Yi-Nan Li, Chi-Shiun Chiang, and Kuo Chu Hwang*, “Engineering Novel Targeted Boron-10 Enriched TheranosticNanomedicine to Combat against Murine Brain Tumors via MR Imaging-Guided Boron Neutron Capture Therapy”, Adv. Mater. 2017,29, 1700850.(SCI IF= 21.9)
  10. Arunachalam Sagadevan, Vaibhav Pramod Charpe, Ayyakkannu Ragupathi, and Kuo Chu Hwang*, “Visible Light Copper Photoredox-catalyzed Aerobic Oxidative Coupling of Phenol and Terminal alkynes: Regioselctive Synthesis of Functionalized Ketones via CºC Triple Bond Cleavage”,J. Am. Chem. Soc2017,139(8), 2896–2899. (SCI IF= 14.3).
  11. Ayyakkannu Ragupathi, Vaibhav Pramod Charpe, Arunachalam Sagadevan, and Kuo Chu Hwang*, Visible light-mediated, Copper(I)-Catalysed Aerobic Oxidation of Ynamides/Ynamines at Room Temperature: A Sustainable Approach to Synthesis of α-Ketoimides/α-Ketoamides, Advanced Synthesis & Catalysis 2017, 359, 1138-1143(SCI IF= 5.6).
  12. Chung-Hsuan Wu, Wei-Han Wang, Chien-Chong Hong*, and Kuo Chu Hwang, A Disposable Breath Sensing Tube with On-Tube Single-Nanowire Sensor Array for On-Site Detection of Exhaled Breath Biomarkers,Lab Chip 2016, 16, 4395–4405. (SCI IF= 6.0).
  13. Poliraju Kalluru, Raviraj Vankayala, Chi-Shiun Chiang, Kuo Chu Hwang,” Unprecedented Multi-Functional Lanthanide-Doped Mesoporous Silica Frameworks for Bimodal Imaging and Chemo-Photodynamic Therapy of Tumors”, Adv. Funct. Mater201626, 7908–7920. (SCI IF= 12.3)
  14. Arunachalam Sagadevan, Vaibhav Pramod Charpe, and Kuo Chu Hwang*, Visible-light-mediated, copper(I)-chloride catalysedCsp-Csphomocoupling of terminal alkynes: More facile for electron withdrawing groups”,Catal. Sci. Technol. 2016, 6, 7688–7692, (SCI IF= 5.7),highlighted in the inside back cover by editor.
  15. Priya Vijayaraghavan, Cheng-Hong Liu, and Kuo Chu Hwang*, Synthesis of Multi-Branched Gold Nanoechinus using a Gemini Cationic Surfactant and its Application for Surface Enhanced Raman Scattering, ACS Appl. Mater. Interfaces 2016, 8, 23909−23919;(SCI IF=8.0)
  16. Ragupathi, Arunachalam Sagadevan, Chun-Cheng Lin, Jih Ru Hwu, and Kuo Chu Hwang*, “Copper(I)-Catalysed Oxidative C-N Coupling of 2-aminopyridine with Terminal alkynes featuring an CºC bond Cleavage promoted by Visible Light”, ChemComm 201652, 11756 – 11759;(SCI IF= 6.3), highlighted in the inside back cover.
  17. Priya Vijayaraghavana, Chi-Shiun Chiang, Huihua Kenny Chiang, Meng-Lin Li, and Kuo Chu Hwang*, “Multi-Branched Gold Nanoechinus-Based Triple Modal Bioimaging: An Efficient NIR-to-NIR Up- and Down-conversion Emission and Photoacoustic Imaging”, Adv. Mater. Technologies 2016, 1, 1600107. (SCI IF= 4.6); hightlighted in the Front cover.
  18. Arunachalam Sagadevan, Ping-Chiang Lyu, and Kuo Chu Hwang*, “Visible-light-activated Copper(I)-catalyzed Oxidative Csp-Csp Cross-Coupling Reaction: Efficient Synthesis of Unsymmetrical Conjugated Diynes without Ligands and Base”, Green Chem 201618, 4526 – 4530;highlighted in the back cover. (SCI IF=8.58)
  19. Sagadevan, A. Ragupathi, K. C. Hwang*,”Visible-light-induced preparation of Functionalized Indoles”, Atlas of Science 2016, June 1 issue.
  20. Poliraju Kalluru, Raviraj Vankayala, Chi-Shiun Chiang, and Kuo Chu Hwang*, Nano-Graphene Oxide-mediatedIn vivo Fluorescence Imaging and Bimodal Photodynamic and Photothermal Destruction of Tumors, Biomaterials 2016, 95, 1-10.. (SCI IF= 8.5) 
  21. Shwu-Chen Tsay *, Shu-Yu Lin, Wen-Chieh Huang, Ming-Hua Hsu, Kuo Chu Hwang, Chun-Cheng Lin, Jia-CherngHorng, I-Chia Chen, Jih Ru Hwu *, Fa-kuen Shieh, Pieter Leyssen, Johan Neyts * “Synthesis and Structure−Activity Relationship of Imidazole–Coumarin Conjugates against Hepatitis C Virus”, Molecules 2016, 21, 228. (SCI IF= 2.41)
  22. Arunachalam Sagadevan, Ayyakkannu Ragupathi, and Kuo Chu Hwang*, VisibleLight-Induced Copper-Catalyzed Three-Component Coupling of Arylamine, Terminal alkynes, and Benzoquinone: One-Step Regio-selective Synthesis of Indoles via C-H Functionalization”, Angew. Chem. Int. Ed.2015, 54, 13896–13901(5-Y IF= 12.1), ranked as “highly important” and “very important”, chosen as HOT paper and highlighted in Frontispiece.
  23. Raviraj Vankayala, Chien Lin Kuo, Karthik Nuthalapati, Chi-Shiun Chiang, Kuo Chu Hwang*, “Nucleus-Targeting Multi-functional Gold Nanoclusters for Simultaneous Fluorescence Imaging, Gene Delivery and NIR Light Activated Photodynamic Therapy” Adv. Funct. Mater201525, 5934–5945;Highlighted in Frontispiece. (SCI IF= 12.3)
  24. Sharada P. Swain, Yi-Chun Shih, Shwu-Chen Tsay, Joby Jacob, Chun-Cheng Lin, Kuo Chu Hwang, Jia-Cherng Horng, and Jih Ru Hwu*, Aryne-Induced Novel Tandem 1,2-Addition/(3+2) Cycloaddition to Generate Imidazolidines and Pyrrolidines, Angew. Chem. Int. Ed. 2015, 54, 9926 –9930. (SCI IF= 12.1)
  25. Jih Ru Hwu*, Mohit Kapoor, Shwu-Chen Tsay, Chun-Cheng Lin, Kuo Chu Hwang, Jia-Cherng Horng, I-Chia Chen, Fa-Kuen Shieh, Pieter Leyssen, Johan Neyts, “Benzouracil–coumarin–arene conjugates as inhibiting agents for chikungunya virus”, Antiviral Research 2015, 118, 103–109.  (SCI IF= 3.8)
  26. Priya Vijayaraghavan, Raviraj Vankayala, Chi-Shiun Chiang, Hsing-Wen Sung, Kuo Chu Hwang*, Complete Destruction of Deep Tissue-Buried Tumors via Combination of Gene Silencing and Gold Nanoechinus-Mediated Photodynamic Therapy”, Biomaterials 2015, 62,13-23.  (SCI IF= 8.4).
  27. Jing-Wun Fan*, Raviraj Vankayala, Chien-Liang Chang, Chia-Hua ChangChi-Shiun Chiang, Kuo Chu Hwang* “ Preparation, Cytotoxicity, and in vivo Bioimaging of Highly Luminescent Water-Soluble Silicon Quantum Dots”, Nanotechnology 2015, 26, 215703 (10pp). (SCI IF= 3.8).
  28. Arunachalam Sagadevan, Ayyakkannu Ragupathi, Chun-Cheng Lin, Jih Ru Hwuand Kuo Chu Hwang* “Visible Light-Initiated Copper(I)-Catalyzed C-N Coupling of Aromatic Amines with Terminal Alkynes: Sustainable One Step Synthesis of α-Ketoamides using Commercial Substrates”, Green Chem. 2015, 17 (2)1113 - 1119. (SCI IF=9.1).
  29. Kuo Chu Hwang*, and ArunachalamSagadevan, “One-Pot Room Temperature Green Conversion of Cyclohexane to Adipic Acid by Ozone/UV Light”, Science 2014, 346, 1495-1498.(5-Y IF=41.0).Highlighted in Chemistry World, Scientific American, C&EN, ScienceNews, Phys.Org, etc.  PDF Link
  30. Kuo Chu Hwang* and Periyasamy Murugan*, “Synthesis of P38 MAP kinase Inhibitor Analogues Compounds and Quinoxalinone Derivatives”, Int. J. Pharma and Bio Sciences 2014, 5(4), 212 -224.
  31. Periyasamy Murugan* and Kuo Chu Hwang*, “Efficient green light-emitting diodes based on substituted triphenylamine derivatives”, Int. J. ChemTech Research 2014, 6 (7), 3518-3526.
  32. Priya Vijayaraghavan, Cheng-Hong Liu, Raviraj Vankayala, Chi-Shiun Chiang, Kuo Chu Hwang*, “Designing Multi-branched Gold Nanoechinus for NIR Light Activated Dual Modal Photodynamic and Photothermal Therapy in the Second Biological Window”, Adv. Mater. 201426, 6689–6695. (5-Y IF=21.9). Highlighted as FrontispieceHighlighted by Asian Scientist magazine.
  33. Avijit K. Adak, Ben-Yuan Li, Li-De Huang, Ting-Wei Lin, Tsung-Che Chang, Kuo Chu Hwang, and Chun-Cheng Lin*“Fabrication of antibody microarrays by lightinduced covalent and oriented immobilization”, ACS Applied Materials & Interfaces 2014, 6, 10452-10460. (SCI IF=7.5).
  34. Raviraj Vankayala, Chi-Shiun Chiang, Chiun-Jye Yuan, Jui-I Chao, Shyr-Yeu Lin, and Kuo Chu Hwang*, “A General Strategy to Achieve Ultra-High Gene Transfection Efficiency using Lipid-Nanoparticle composites”, Biomaterials 2014, 35(28), 8261-8272. (SCI IF= 8.4).
  35. Raviraj Vankayala, Chun-Chih Lin, PolirajuKalluru, Chi-Shiun Chiang, and Kuo Chu Hwang*, “Gold Nanoshells-Mediated Bimodal Photodynamic and Photothermal Cancer Treatment Using Ultra-Low Doses of Near Infra-red Light”,Biomaterials 2014, 35(21), 5527-5538. (SCI IF= 8.4)
  36. Raviraj Vankayala, Yu-Kuan Huang, Poliraju Kalluru, Chi-Shiun Chiang, Kuo Chu Hwang*, “First Demonstration of Gold Nanorods-Mediated Photodynamic Therapeutic Destruction of Tumors via Near Infra-Red Light Activation”, Small 2014, 10(8), 1612–1622. (SCI IF= 8.6), Highlighted by Nanowerk, Future Med Chem. (2014) 6(4), 370 and The #1 Antibody Resource website.
  37. Raviraj Vankayala, Poliraju Kalluru, Hsin-Hui Tsai, Chi-Shiun Chiang, and Kuo Chu Hwang*,“Effects of Surface Functionality of Carbon Nanomaterials on Short-Term Cytotoxicity and Embryonic Development in Zebrafish“, J. Mater. Chem. B 2014, 2 (8), 1038 - 1047(5-Y IF= 4.72)
  38. Shengqin Wang, Zi-Xiang Lin, Wei-Han Wang, Chien Lin Kuo, Kuo Chu Hwang*, Chien-Chong Hong*, Self-regenerating Photocatalytic Sensor Based on Dielectrophoretically Assembled TiO2 Nanowires for Chemical Vapor Sensing”,. Sensors and Actuators B: Chem. 2014, 194, 1– 9.(SCI IF=3.83).
  39. Chin-Feng Wan*, Chao-Sheng Chen, Kuo-Chu Hwang, Yen-Han Lai, Jhang-Yun Luo, Po-Ching Liu, Long-Sheng Fan*, “Development and Automation of Microelectromechanical Systems-Based Biochip Platform for Protein Assay”, Sensors & Actuators B: Chem2014, 193, 53-61.(SCI IF=3.83).
  40. Poliraju Kalluru, Raviraj Vankayala, Chi-Shiun Chiang‍‍, Kuo Chu Hwang*,”Photo-sensitization of singlet oxygen and Photodynamic Therapeutic Effects Mediated by PEGylated W18O49 Nanowires on Destruction of Tumors”Angew. Chem. Int. Ed. 2013, 52(47), 12332-12336.Highlighted in inside back cover. (5-Y IF= 11.99).
  41. Arunachalam Sagadevan, Ayyakkannu Ragupathiand Kuo Chu Hwang*“Visible-light Induced Copper (I) Catalyzed Oxidative Diamination of Terminal Alkynes by o-Phenylenediamine: One-Pot Synthesis 3-Phenyl-2-hydroxy-quinoxaline”, Photochem. Photobiol. Sci. 2013, 12 (12)2110 - 2118, (SCI IF= 2.92) invited paper in a memorial issue dedicated to the late professor N. J. Turro, 
  42. Raviraj Vankayala, Chien-Lin Kuo, Arunachalam Sagadevan, Po-Hung Chen, Chi-Shiun Chiang and Kuo Chu Hwang*, “Morphology Dependent Sensitization and Formation of Singlet Oxygen (1Δg) by Gold and Silver Nanoparticles and its Application in Cancer Treatment”, J. Mater. Chem. B. 2013, 1, 4379-4387.(5-Y IF= 4.72), selected as HOT article by editor for 2013.
  43. Shwu-Chen Tsay, Jih Ru Hwu, Raghunath Singha, Wen-Chieh Huang, Yung Hsiung Chang, Ming-Hua Hsu, Fa-kuen Shieh, Chun-Cheng Lin, Kuo Chu Hwang, Jia-CherngHorng, Erik De Clercq, IngeVliegen, Johan Neyts, “Coumarins hinged directly on benzimidazoles and their ribofuranosides to inhibit hepatitis C virus”, Euro. J. Med. Chem. 2013, 63, 290-298.  (SCI IF= 3.43) 
  44. Congxin Dai, Feng Cai, Kuo Chu Hwang, Yongmao Zhou, Zizhu Zhang, Xiaohai Liu, Sihai Ma, Yakun Yang, Yong Yao, Ming Feng, XinjieBao, Guilin Li, Junji Wei, Yonghui Jiao, Zhenqing Wei, Wenbin Ma, Renzhi Wang, "Folate receptor-mediatedboron-10 containing carbon nanoparticles as potential delivery vehicles for boron neutron capture therapy of nonfunctional pituitary adenomas”, Science China Life Sciences 2013, 56(2), 163-173.(SCI IF= 1.345).
  45. Chein Lin Kuo, and Kuo Chu Hwang* “ Does Morphology of a Metal Nanoparticle Play a Role in Ostwald Ripening Processes?”, Chem. Mater. 2013, 25(3), 365-371. (SCI IF= 9.46).
  46. Arunachalam Sagadevan, and Kuo Chu Hwang*, “Photo-induced Sonogashira C-C Coupling Reaction Catalyzed by Simple CuCl Salt at Room Temperature”Advanced Synthesis & Catalysis 2012, 354 (18), 3421-3427(SCI IF=5.6).
  47. K. S. Prasad, Nien-Chu Fan, Li-Chen Wu, Heng-Chia Chang, Li-Sheng Wang, Kuo-Chu Hwang, Reuben Jih-Ru Hwu, Jia-CherngHorng, Chun-Cheng Lin and Ja-an Annie Ho*, “A Tunable Multicolor Photoluminescent Nanocarbon Prepared from Castor Oil Soot”, J. Chin. Chem. Soc. 201259, 802-808.(SCI IF= 0.65).
  48. Z. Y. Lien, T. C. Hsu, K. K. Liu, W. S. Liao, K. C. Hwang, and J. I. Chao*, “Cancer cell labeling and tracking using fluorescent and magnetic nanodiamond”, Biomaterials 2012, 31, 6172-6185.(5-Y IF= 8.97).
  49. Pradip Kundu, and Kuo Chu Hwang*, “Rational Design of Phosgene Fluorescence Sensors”, Anal. Chem2012,84, 4594-4597. (5-Y IF= 5.79)Highlighted by C&EN, 2012-04-17.5-Y IF=5.98.
  50. Chien Lin Kuo, and Kuo Chu Hwang*, "Self-Assembly of Silver Nanoparticles and Nanorods to Form Strained Long Nanowires: A New Nanowire Growth Mechanism",Langmuir 2012, 28, 3722-3729.(SCI IF= 4.18).
  51. Chung-Liang Wang, Lan-Yi Wei, Chiun-Jye Yuan* and Kuo Chu Hwang, “Reusable amperometric biosensor for measuring protein tyrosine kinase activity”, Anal. Chem2012, 84, 971-977. (5-Y IF=5.79)
  52. Chun-Chih Chang, L. W. Wang, Y. H. Chen, Kuo Chu Hwang, Jwo-Huei Jou, Y. S. Chang, Arnold C.-M. Yang*, “White Luminescent Polymers by Plasma Polymerized Iridium Complexes from 1,10-phenanthrolin”. Plasma Process Polym2012, 9, 225-233. (SCI IF=2.46).
  53. Raviraj Vankayala, Arunachalam Sagadevan, Priya Vijayaraghavan, Chien Lin Kuo, Kuo Chu Hwang*, “Metal Nanoparticles Sensitize Formation of Singlet Oxygen”, Angew. Chem. Int. Ed . 201150, 10640-10644. (5-YIF= 12.1).
  54. K. P. Tung, C.-H. J. Tsao, T. M. Hong, K. C. Hwang, J.-H. Hsu, J. D. White, and A. C. M. Yang*, Dramatic Photoluminescence Enhancements of Conjugated Polymers by Molecular Constraints via Mechanical Stretching, ACS Nano 20115, 7296-7302. (5-YIF= 14.48).
  55. Raviraj VankayalaWei-jen Petrick Lai, Kuo-Chung Cheng, and Kuo Chu Hwang*, "Enhanced electrical conductivity of nylon 6 composite using polyaniline-coated multi-walled carbon nanotubes as additives", Polymer 2011, 52, 3337-3343. (SCI IF= 3.8).
  56. Chun-Chih Chang, Yi-Hsin Chang, Kuo Chu Hwang, Jwo-Huei Jou, Arnold C.-M. Yang*, “One-step fabrication of π-conjugated polymer thin films from naphthalenes via plasma polymerization for efficient optoelectronic devices: white polymer light-emitting diodes”. Plasma Process Polym. 2011, 8, 215-223. (SCI IF=2.46).
  57. C. C. Chen, W. Hsu., K. C. Hwang, J. R. Hwu, C. C. Lin, J. C. Horng*, Contributions of Cation-pi interactions to the collagen triple helix stability. Arch. Biochem. Biophys. 2011, 508, 46-53. (SCI IF= 3.046).
  58. Lin Ai Tai and Kuo Chu Hwang* “Regulation of Xanthine Oxidase Activity by Substrates at Active Sites via Cooperative Interactions between Catalytic Subunits: Implication to Drug Pharmacokinetics”, Current Medicinal Chemistry 2011, 18, 69-78(SCI IF= 4.85).
  59. Chiun-Jye Yuan*, Chung-Liang Wang, Teng Yang Wu, Kuo Chu Hwang, and Wei-Chi Chao. Fabrication of a carbon fiber paper as the electrode and its application toward developing a sensitive unmediated amperometric biosensor. Biosensors andBioelectronics 2011, 26, 2858-2863. (SCI IF= 5.6)
  60. Kuo Chu Hwang*, "Recent Progress in the Preparation and Applications of Carbon Nanoocapsules", J. Phys. D: Appl. Phys. 201043, 374001 (13pp) (invited review). (SCI IF= 2.1).
  61. Kuo Chu Hwang*, Po Dong Lai, Chi-Shiun Chiang, Pei-Jen Wang, Chiun-Jye Yuan "Neutron Capture Elements-Containing Carbon Nanoparticles for Destruction of Cancer Cells ", Biomaterials 2010, 31,8419-8425.(5-Y IF= 8.97).
  62. Chang-Ching Lin, Nai-Pin Lin, L. Sk Sahabuddin, Vijaya Raghava Reddy, Li-De Huang, Kuo Chu Hwang, and Chun-Cheng Lin*,”5-N,4-O-Carbonyl-7,8,9-tri-O- chloroacetyl-Protected Sialyl Donor fortheStereoselective Synthesis of r-(2f9)-Tetrasialic Acid”, J. Org. Chem. 2010, 75(15), 4921-28. (SCI IF= 4.21)
  63. Qingxin Mu, Lei Yang, James C. Davis, Raviraj Vankayala, Kuo Chu Hwang, Jincai Zhao and Bing Yan* “Biocompatibility of Polymer Grafted Core/Shell Iron/Carbon NanoparticlesBiomaterials 2010, 31, 5083-5090. (5-Y IF= 8.97).
  64. Ja-an Annie Ho, Li-ChenWu, Li-Hui Chang, Kuo Chu Hwang, Jih-Ru Reuben Hwu“Liposome-based immunoaffinity chromatographic assay for the quanitation of immunoglobulin E in human serum”, J. Chromatography B-Analytical Technologies in The Biomedical and Life Sci2010, 878, 172-176.  (SCI IF= 2.50).
  65. In Pin Chang, Kuo Chu Hwang*, Ja-an Annie Ho, Chun-Cheng Lin, Reuben J.-R. Hwu, Jia-Cherng Horng, "Facile Surface Functionalization of Nanodiamonds", Langmuir2010, 26(5), 3685–3689. (SCI IF=4.0).
  66. Kuo Chu Hwang*, "Light-absorbing Materials and Applications", Taiwan patent application number: 094130138, patent allowed, Oct. 18, 2009
  67. Huang, J. J.-T.; Tsai, F.-Y.; Tsay, S.-C.; Hsu, M.-H.; Hwang, K. C.; Horng, J.-C.; Ho, J. A.; Lin, C.-C.; Hwu, J. R.* "Photochemical Activities of N-Nitroso Carboxamides and Sulfoximides as well as Their Application to DNA Cleavage" Chem. Euro. J2009, 15, 8742-8750. (SCI IF= 5.92). Cover page article.
  68. Ja-an Annie Ho*, Yeh-Chun Lin, Li-Sheng Wang, Kuo Chu Hwang, Pi-Tai Chou, "Carbon Nanoparticle Enhanced Immunoelectrochemical Detection for Protein Tumor Marker with Cadmium Sulfide Biotracers", Anal. Chem. 2009, 81, 4, 1340-1346. (SCI IF= 5.85).
  69. Ho, J.-A. A.*; Chiu, J.-K; Hsu, W.-L.; Hong, J.-C.; Lin, C. C.; Hwang, K.-C.; Hwu, J. R. "Gold-Nanostructured Immunosensor for the Electrochemical Sensing of Biotin Based on Liposomal Competitive Assay" J. Nanosci. Nanotech. 20099, 2324-2329. (SCI IF 1.56).
  70. Mu-Lin Chen, Avijit Kumar Adak, Nai-Chia Yeh, Wen-Bin Yang, Yung-Jen Chuang, Chi-Huey Wong, Kuo Chu Hwang, Jih-Ru Reuben Hwu, Shih-Liang Hsieh, Chun-Cheng Lin*, "Fabrication of an Oriented Fc-Fused Lectin Microarray through Boronate Formation",AngewChemInt Ed Engl200847, 8627-8630. (5-Y IF= 12.1)
  71. In Pin Chang, Kuo Chu Hwang*, Chi-Hsin Chiang, "Preparation of Fluorescent Magnetic Nanodiamonds and Cellular Imaging", J. Am. Chem. Soc. 2008,130, 15476-15481. (SCI IF 9.9) Highlighted in Nature Publishing Group (NPG) Asia Materials for the best research published in the field of materials science by researchers in the Asia-Pacific region, Dec 2008.
  72. Yu-Lin Hsin, Chia-Fen Lin, Yu-Chia Liang, Kuo Chu Hwang*, Jia-CherngHorng, Ja-an Annie Ho, Chun-Cheng Lin, Reuben J.-R. Hwu, "Microwave Arcing Induced Formation and Growth Mechanisms of Core-shell Metal/carbon Nanoparticles in Organic Solutions", Adv. Funct. Mater.200818, 2048--2056. (SCI IF= 10.17) Cover page article.
  73. Yu-Chia Liang, Kuo Chu Hwang*, Shen-Chuan Lo, "Solid State Microwave Arcing Induced Formation and Surface Functionalization of Core-Shell Metal/Carbon Nanoparticles.", Small 20084, 405-409. (5-Y IF= 8.3)
  74. Yu Lin Hsin, Kuo Chu Hwang* and Chuin-TihYeh, “Poly(vinyl pyrrolidone) Modified Graphite Carbon Nanofibers as Promising Supports for PtRu Catalysts in Direct Methanol Fuel Cells.”, J. Am. Chem. Soc2007, 129, 9999-10010. (SCI IF 9.9)Times Cited:309
  75. Chun Chih Tong, and Kuo Chu Hwang*, "Enhancement of OLED Efficiencies and High Voltage Stabilities by Deuteration of Light Emitting Materials ", J. Phys. Chem. C. 2007. 111, 3490-3494.  (SCI IF= 4.8)
  76. Qin-Hua Song, Kuo Chu Hwang*, "Direct observation for photophysical and photochemical processes of folic acid in DMSO solution", J. Photochem. Photobiol. A: Chem. 2007, 185, 51–56. (SCI IF 2.286)
  77. Kuo Chu Hwang*, Yu Lin Hsin, Jyun-Yi Lai, "Application of nano-materials in biomedical diagnosis", Chemistry (The Chinese Chem. Soc. Taipei) June 2006, 64 (2), 179-190. (invited review).
  78. Yu Lin Hsin, Jyun-Yi Lai, Kuo Chu Hwang*Shen-Chuan Lo, Fu-Rong Chen, and J. J. Kai, "Rapid Surface Functionalization of Fe-Filled Multi-walled Carbon Nanotubes", Carbon 2006, 44, 3328-3335. (SCI IF 5.37).
  79. P. Murugan, Kuo Chu Hwang, V. T. Ramakrishnan and S. Balasubramanian, " Facile Synthesis of Electroluminescence Acridinedions by Microwave and Ultrasound", AZojomo-J. Materials online, 2005, 1, 1-7.
  80. Yeong-Tarng Shieh*, Gin-Lung Liu, Kuo Chu Hwang, and Chia-Chun Chen," Enhancement of PEO Crystallization in PEO/MWNTs-g-PMMA Blends", Polymers 2005, 46, 10945-10951.(SCI IF 3.43).
  81. Shu-Wen Yang, Arumugasamy Elangovan, Kuo Chu Hwang, and Tong-Ing Ho*," Electronic Polarization Reversal and Excited State Intramolecular Charge Transfer in Donor/Acceptor EthynylPyrenes", J. Phys. Chem. B 2005, 109, 16628-16635. (SCI IF 3.69)
  82. Periyasamy Murugan, Kuo Chu Hwang, Dhakshanamurthy Thirumalai*, and Vayalakavoor T. Ramakrishnan, "A facil and simple route to the synthesis of condensed acridine systems", Synthetic Comm. 2005, 35, 1781-1788.  (SCI IF 1.06).
  83. Y.-L. Chen, S.-W. Lee, Y. Chi*, Kuo Chu Hwang, S. B. Kumar, Y.-H. Hu, Y.-M. Cheng, P.-T. Chou, S.-M. Peng, G.-H. Lee, C.-T. Chen and S.-J. Yeh, "Synthesis, Characterization and Photophysical Properties of Os(II) Diimine Complexes [Os(N^N)(CO)2I2], NN = Bipyridine, Phenanthroline and PyridylBenzoxazole", Inorg. Chem2005, 44, 4287-4294. (SCI IF 4.12).
  84. U-SerJeng*, Chia-Hung Hsu, Tsang-Lang Lin, Ching-Mao Wu, Hsin-Lung Chen, Lin-Ai Tai, and Kuo Chu Hwang, "Dispersion of fullerenes in phospholipid bilayers and the subsequent phase changes in the host bilayers", Physica B: Physics of Condensed Matter, 2005, 357, 193-198. (SCI IF 1.06).
  85. Gan Lin Hwang, Yeong-Tarng Shieh*, Kuo Chu Hwang*, “Efficient load transfer to polymer chain grafted carbon nanotubes in composite polymers”, Adv. Functional Mater. 2004,14(5), 487-491.  (SCI IF 9.76) Times Cited: 194
  86. Lin Ai Tai, Kuo Chu Hwang*, “Cooperative Inhibition in Xanthine Oxidase Homodimer Subunits”, Biochemistry 200443, 4869. (SCI IF 3.42)
  87. Ya-Wen Chen, Kuo Chu Hwang, Cheng-Chieh Yen, and Yih-Loong Lai*, “Fullerene derivatives protect against oxidative stress in RAW 264.7 cells and ischemia-reperfused lungs”, Am J PhysiolRegulIntegr Comp Physiol, 2004,287: R21-R26. (SCI IF 3.33)
  88. P. Murugan, Kuo Chu Hwang*, V. T. Ramakrishnan, S. Balasubramanian, “Facile Synthesis of Electroluminescence Materials, Acridinediones”, Advances in Technology of Materials and Materials Processing Journal 2004, 6(1), 37-42.
  89. Aminul Islam, Periyasamy Murugan, Kuo Chu Hwang*, Chien-Hong Cheng, “Blue light-emitting devices based on 1,8-acridinedione derivatives”, Synthetic Metals 2003,139 (2), 347-353.  (SCI IF 1.82)
  90. Gan Lin Hwang, Kuo Chu Hwang*, Yeong-Tarng Shieh, S. J. Lin “ Preparation of carbon nanotubes encapsulated copper nanowires and their use as a reinforcement for Y-Ba-Cu-O superconductors”, Chem. Mater. 2003, 15, 1353-1357. (5-Y IF=9.3)
  91. Sudhir Ranjan, Shen Yi Lin, Kuo Chu Hwang*, Yun Chi*, Wei-Li Ching, Chao-Shiuan Liu, Yu-Tai Tao, Chin-Hsiung Chien, Shie-Ming Peng and Gene-Hsiang Lee“Realizing Green Phosphorescent Light-Emitting Materials from Rhenium(I) Pyrazolato Diimine Complexes”,Inorg. Chem2003, 42, 1246-1255. (SCI IF 4.6) Times Cited: 140
  92. Y.-L. Lai, P. Murugan, K.C. Hwang*, “Fullerene derivative attenuates ischemia-reperfusion-induced lung injury”, Life Sci. 72: 1271-1278, 2003. (SCI IF 2.52)
  93. Q. H. Song &K. C. Hwang*, “Reaction Mechanism of Photoenzymes”, Chemistry (The Chin Chem. Soc., Taipei, in Chinese, invited review), 2002, 60, 621-629.
  94. S. F. Tzeng*, J. L. Lee , J. S. Kuo, C. S. Yang, P. Murugan, L. A. Tai, K. C. Hwang, "Effects of malonate C-60 derivatives on activated microglia", Brain Research 2002, 940 (1-2): 61-68. (SCI IF 2.72).
  95. Sen Chin Kung, Kuo Chu Hwang*, I. N. Lin,“O2 and O3 Oxidation Enhanced Field Emission of Carbon Nanotubes, Appl. Phys. Lett2002, 80, 4819-4821. (SCI IF 3.84).
  96. Kuo Chu Hwang*, “Carbon nanotubes as field emitters for flat panel displays”, Chemical Engineering 2002, 49(1), 43-52. (Invited review).
  97. Che-Hao Chang, Kuo Chu HwangChao-Shiuan Liu, Yun Chi*, Arthur J. Carty, LudmilaScoles, Shie-Ming Peng, Gene-Hsiang Lee, and Jan Reedijk, “Unique formation and stabilization of a decanuclear Cu(II) wheel linked by chloride and O¼H-N Hydrogen bonds”, Angew. Chem. Int. Ed. Engl2001, 40, 4651-4653. (SCI IF 13.45).
  98. Ing Che Kao, Yu Lin Hwang, Cheu-Pyeng Cheng, Wen-Jwu Wang, Bo-Cheng Wang, Kuo Chu Hwang*, "Production of Carbon Nanotubes in Air”, Fullerene Science & Technology 20019 (3), 321-328. (SCI IF 0.85)Times Cited:3
  99. Gan Lin Hwang, Kuo Chu Hwang*, "Breakage, Fusion, and Healing of Carbon Nanotubes, Nano Lett. 2001, 1, 435-438. (SCI IF 13.2).
  100. Y. L. Hsin, K. C. Hwang*, Fu-Rong Chen, J. J. Kai, "Production and in situ metal filling of carbon nanotubes in water", Adv. Mater. 2001, 13, 830-833. (SCI IF 13.87) Times Cited: 129
  101. Gan Lin Hwang, Kuo Chu Hwang*, "Carbon Nanotubes Reinforced Ceramics", J. Mater. Chem2001, 11, 1722-1725. (SCI IF 5.96)
  102. Lin Ai Tai, Kuo Chu Hwang*, "Photo Reactivation of Alloxanthine Inhibited Xanthine Oxidase", Photochem. Photobiol.2001, 73, 439-446. (SCI IF 2.41).
  103. Kuo Chu Hwang*, “ Development and Applications of Carbon Nanotubes” (invited paper, in Chinese), Natural Sciences Newsletter, NSC 2000,12(2), 60-62.
  104. D. Samuel, T. K. S. Kumar, G. Ganesh, G. Jayaraman, P. W. Yang, V. Trivedi, S. L. Wang, K. C. Hwang, D. K. Chang, C. Yu*, "Proline Inhibits Aggregation during Protein Refolding", Protein Science2000, 9(8), 1604-1604. (SCI IF 2.79)
  105. Lin Ai Tai, Kuo Chu Hwang*, "Control of Xanthine Oxidase Activity by Light", Angew. Chem. Int. Ed. Engl., 2000, 39 (21), 3886-3888.  (SCI IF 13.4)
  106. D. Samuel, T. K. S. Kumar, G. Ganesh, G. Jayaraman, P. W. Yang, V. Trivedi, S. L. Wang, K. C. Hwang, D. K. Chang, C. Yu*, "Proline Inhibits Aggregation during Protein Refolding”, Protein Science2000, 9(2), 344-352. (SCI IF 2.79)Times Cited: 153
  107. I Chen Wang, Lin Ai Tai, Don Dar Lee, P. P. Kanakamma, Clifton, K. -F. Shen, TienYauLuh, Chien Hong Cheng, Kuo Chu Hwang*,"C60 and Water Soluble fullerene Derivatives as Antioxidants against Radical Initiated Lipid Peroxidation", J. Med. Chem., 1999, 42, 4614-4620. (SCI IF 5.24) Times Cited: 176
  108. Y. L. Hwang, and K. C. Hwang*, “Nonlinear Stern-Volmer fluorescence quenching of pyrene by C60/70",FULLERENE SCIENCE AND TECHNOLOGY1999, 7(3), 437-454. (SCI IF 1.0).
  109. Yu-Lun Huang, Clifton K. F. Shen, Tien-YauLuh, Hong Chou Yang, Kuo Chu Hwang, Chen Kung Chou*,"Selective Blockage of Apoptotic Signaling of Transforming Growth Factor-b by Bcl-2 and Carboxyfullerene in Human Hepatoma cells", Euro. J. Biochem. 1998, 254, 38-43.   (SCI IF 3.25)
  110. Yu Lien Hwang, and Kuo Chu Hwang*, "Photophysical and Photochemical Studies of C60 by ESR spectroscopy" (invited paper, in Chinese), Chemistry (The Chinese Chem. Soc., Taipei) 1997, 55, pp53-58.
  111. Yu Lien Hwang, CheChau Yang, and Kuo Chu Hwang*, "Origin of the Spike in the C60-. ESR Spectrum: Oxygen Effect and Negative Temperature Dependence of the C60O2-. Isomerization Rate", J. Phys. Chem1997, 101, 7971-7976. (SCI IF 2.94)
  112. Kuo Chu Hwang*, “Developments of Molecular Electronics" (invited paper, in Chinese), Natural Science Newsletter, NSC1996, 8(1) 16-19.
  113. C. C. Yang, and K. C. Hwang*, “Disproportionation of Photo Excited C60", J. Am. Chem. Soc1996, 118, 4693. (SCI IF 9.9)
  114. K. C. Hwang*, “Efficient cleavage of carbon graphene layers by oxidants", J. Chem. Soc. Chem. Comm.1995, 173.
  115. K. C. Hwang*, “High yield conversion of carbon nanotubes to nanostraws at mild conditions", SCIENCE AND TECHNOLOGY OF FULLERENE MATERIALS  Book Series: MRS SYMPOSIUM PROCEEDINGS   Volume: 359   Pages: 75-80   Published: 1995.
  116. K. C. Hwang, S. Niu, D. Mauzerall*, Electron Transfer Across a Lipid Bilayer Mediated by Fullerenes.  In Recent Advances in the Chemistry and Physics of Fullerenes and Related Materials.  K. M. Kadish, and R. S. Ruoff, Eds., The Electrochemical Society, Inc., Pennington, NJ, 1994, pp845~853.
  117. K. C. Hwang*, N. J. Turro*, and H. D. Roth,"Hydrogen donating solvent participation in the photochemistry of benzaldehyde and deoxybenzoin- A 13C CIDNP study", J. Org. Chem. 1994, 59, 1102-1107.  (SCI IF 4.45)
  118. K. C. Hwang, D. Mauzerall*, R. W. Wagner, and J. S. Lindsey, "Synthesis of amphipathic porphyrins and their photoinduced electron transfer reactions at the lipid bilayer-water interface", Photochem. Photobiol. 1994, 59, 145-151.(SCI IF 2.41)
  119. K. C. Hwang, and D. Mauzerall*, “PhotoinducedTransmembrane Electron Transport Mediated by C70 Anion", Nature1993361, 138. (SCI IF 36.28), Times Cited: 140
  120. K. C. Hwang, and D. Mauzerall*, “Vectorial Electron Transfer from an Interfacial Photoexcited Porphyrin to Ground State C60 and C70 and from Ascorbate to Triplet C60 and C70 in a Lipid Bilayer", J. Am. Chem. Soc. 1992, 114, 9705.  (SCI IF 9.9), Times Cited: 78
  121. K. C. Hwang, H. D. Roth, N. J. Turro*, and K. M. Welsh, “Enhancement or Suppression of CIDNP Intensities by a 2nd Magnetic Nucleus-Interplay between g-Factor Defference External Magnetic Field, and Hyperfine Coupling Constants”, J. Phys. Org. Chem. 19925, 209.  (SCI IF 1.96)
  122. N. Han, K. C. Hwang, X. Lei, and N. J. Turro*, “Photochemistry of 2,2',12-Trimethyl- cyclododecanone and 2,2',12,12'-tetramethylcyclododecanone: Product Distribution, Photo-CIDNP, and Magnetic Isotope Effect", J. Photochem..Photobiol. A. Chem., 199161, 35. (SCI IF 2.41)
  123. N. J. Turro*, K. C. Hwang, V. P. Rao, and C. Doubleday, Jr., “Utilization of Radical Scavenging to Develop Nuclear Spin Polarization and Magnetic Isotope Separation in Long Flexible Biradicals”, J. Phys. Chem199195, 1872.  (SCI IF 4.17)
  124. K. C. Hwang, N. J. Turro*, and C. Doubleday, Jr., “Investigation of the Kinetic Window for Generationof13C T0 - S CIDNP Derived from Long-Chain Biradicals by Tuning the Rates of Bimolecular Scavenging and Intersystem Crossing”, J. Am. Chem. Soc1991113, 2850.  (SCI IF 9.9)
  125. K. C. Hwang, N. J. Turro*, C. H. D. Roth, and C. Doubleday, Jr., “Suppression of Chemically Induced Dynamic Nuclear Polarization Enhancements by Nuclei with Large Hyperfine Coupling Constants”, J. Phys. Chem199195, 63.  (SCI IF 4.17)
  126. H. D. Roth, R. S. Hutton, K. C. Hwang, N. J. Turro*, and K. M. Welsh, “Chemically Induced Dynamic Nuclear Polarization in Systems Containing Large Hyperfine Coupling Constants”, J. Phys. Chem.198993, 5697.  (SCI IF 4.17)
  127. N. J. Turro*, C. Doubleday, Jr., K. C. Hwang, C. C. Cheng, and J. R. Fehlner, “Magnetic Isotope Effects in Biradicals:  Substantial 13C Enrichment and a Novel Mechanistic Probe”, Tetrahedron Lett., 198728, 2929.  (SCI IF 2.68)
  128. K. S. Arora, K. C. Hwang, and N. J. Turro*, “Photophysical Investigation of the Interactions of Phospholipids and a Pyrene Substitute Poly   (acrylic acid) in Dilute Solutions”, Macromolecules1986, 19, 2806.  (SCI IF 5.16)
  129. Kuo Chu Hwang*, “ Application of Simplex Optimization Technique in Chemical Data Processing, Instruments Today 19856(4), 45-53. (invited paper, in Chinese)
  130. H. Chang* and K. C. Hwang, “The Behavior of Pyridine, Pyridinium Ion, and Pyridinium Halide on a Ag Electrode and Their SERS Spectra”, J. Am. Chem. Soc., 1984106, 6586.  (SCI IF 9.9)
  131. K. C. Hwang and H. Chang*, “The SERS of Pyridine on an Electro-chemically Plated Silver Electrode”, Chem. Phys. Lett.198398, 597.(SCI IF 2.33)


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