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Department of Chemistry
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Uang, Biing-Jiun
Title: Professor                                              Chinese Version

Education:

Yale University(USA)(Ph.D.) (1984)
National Tsing Hua University(M.S.) (1979)
Tamkang University(B.S.) (1975)

Office: Chemistry Building R708
Phone number: 33410
E-mail: bjuang@mx.nthu.edu.tw
Web site: http://aslab.chem.nthu.edu.tw

Professional Experience:

1990 ~
1985 ~ 1990
1984 ~ 1985

Professor of NTHU
Associate Professor of NTHU
Postdoctoral Research, California Institute of Technology

Research Interest:

Organic Synthesis; Natural Product Synthesis; Asymmetric Synthesis


Publications:(After 2009)


  1. Wu, P.-Y.; Wu, H.-L.; Shen, Y.-Y.; Uang,* B.-J. “Asymmetric synthesis of propargylic alcohols catalyzed by (-)-MITH” Tetrahedron:Asymmetry 2009, 20, 1837.
     
  2. Wu, Z.-L.; Wu, H.-L.; Wu, P.-Y.; Uang,* B.-J. “Asymmetric addition of diethylzinc to aldehydes catalyzed by camphor-derived beta-amino alcohol” Tetrahedron:Asymmetry 2009, 20, 1556.
     
  3. Coumar, M.-S.; Tsai, M.-T.; Chu, C.-Y. ; Uang, B.-J.; Lin, W.-H. ; Chang, C.-Y. ; Chang, T.-Y. ; Leou, J.-S. ; Teng, C.-H.; Wu, J.-S.; Fang, M.-Y.; Chen, C.-H.; Hsu, J. T.-A.; Wu, S.-Y.; Chao, Y.-S.; Hsieh, H.-P. “Identification, SAR Studies, and X-ray Co-crystallographic Analysis of a Novel Furanopyrimidine Aurora Kinase A Inhibitor” ChemMedChem 2010, 5, 255.
     
  4. Chen, J.-C.; Uang, B.-J.; Lyu, P.-C.; Chang, J.-Y.; Liu, K.-J.; Kuo, C.-C.; Hsieh, H.-P.; Wang, H.-C.; Cheng, C.-S.; Chang, Y.-H.; Chang, M. D.-T.; Chang, W. S.-W.; Lin, C.-C. “Design and Synthesis of alpha-Ketoamides as Cathepsin S Inhibitors with Potential Applications against Tumor Invasion and Angiogenesis” J. Med. Chem. 2010, 53, 4545.
     
  5. Thangaraj, S.; Tsao, W.-S.; Luo, Y.-W.; Lee,* Y.-J.; Chang, C.-F.; Lin, C.-C.; Uang, B.-J.; Yu, C.-C.; Guh, J.-H.; Teng, C.-M. “Total synthesis of moniliformediquinone and calanquinone A as potent inhibitors for breast cancer” Tetrahedron 2011, 67, 6166.
     
  6. Chu, C.-Y.; Hsu, C.-T.; Uang,* B.-J. “Enantioselective silylcyanation of aldehydes catalyzed by new chiral oxovanadium complex” Tetrahedron:Asymmetry 2011, 22, 1981.
     
  7. Cheng, Y.-N.; Wu, H.-L.; Wu, P.-Y.; Shen, Y.-Y.; Uang,* B.-J. “Enantioselective Addition of Dialkylzincs to Aldehydes Catalyzed by (-)-MITH” Chem. Asian J. 2012, 7, 2921.
     
  8. Tseng, C.-H.; Hung, Y.-M.; Uang,* B.-J. “Enantioselective conjugate addition of dialkylzincs to a,b-unsaturated enones catalyzed by Ni(acac)2 and (+)-(1S,2R)-7,7- dimethyl-1-morpholinoisonorborneol” Tetrahedron:Asymmetry 2012, 23, 130.
     
  9. Hsu,* C.-Y.; Lee, I.-C.; Lico, L.-S.; Uang,* B.-J.; Hung,* S.-C. “Synthesis of a Furanosyl-pyranone Derivative Related to the Tri-O-heterocyclic Core of Herbicidins” J. Chin. Chem. Soc. 2012, 59, 421.
     
  10. Hsu, F.-L.; Huang, C.-F.; Chen, Y.-W. ; Yen, Y.-P.; Wu, C.-T.; Uang, B.-J.; Yang, R.-S.; Liu, S.-H. “Antidiabetic Effects of Pterosin A, a Small-Molecular-Weight Natural Product, on Diabetic Mouse Models” DIABETES 2013, 62, 628.
     
  11. Hsu, S.-C. ; Narsingam, M. ; Lin, Y.-F. ; Hsu, F.-L. ; Uang,* B.-J. “Synthesis of (+/-)-pterosin A via Suzuki-Miyaura cross-coupling reaction” Tetrahedron 2013, 69, 2572.
     
  12. Hsu, J.-L.; Lee, Y.-J. ; Leu, W.-J.; Dong, Y.-S.; Pan, S.-L.; Uang, B.-J.; Guh,* J.-H. “Moniliformediquinone Induces In Vitro and In Vivo Antitumor Activity through Glutathione Involved DNA Damage Response and Mitochondrial Stress in Human Hormone Refractory Prostate Cancer” J. UROLOGY 2014, 191, 1429.
     
  13. Wu, H.-H.; Hsu, S.-C.; Hsu, F.-L.; Uang,* B.-J. “Asymmetric Synthesis of (–)-Pterosin N from a Chiral 1,3-Dioxolanone” Eur. J. Org. Chem. 2014, 4351.
     
  14. Huang, Y.-C.; Uang,* B.-J. “Remote Sulfonamido Group Enhanced Reactivity and Selectivity for Asymmetric Michael Addition of Nitroalkanes to a,b-Unsaturated Aldehydes” Chem. Asian J. 2014, 9, 2444.

 

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